Journal of Advanced Materials in Engineering

Journal of Advanced Materials in Engineering

Synthesis and Characterization of Composite Coating of Iron Oxide and Bioactive Glass, Coated by Electrophoretic co-Deposition Method for Biomedical Applications

Document Type : Original Article

Authors
M. S. Abbasi 1
A. Bahrami 1
A.S. Hosseini-Abari 2
F. Yousef Saber 2
1 Department of Materials Engineering, Isfahan University of Technology, Isfahan 84156-83111, Iran
2 Department of Cell and Molecular Biology & Microbiology, Faculty of Biological Science & Technology, University of Isfahan, Isfahan 8174673441, Iran
10.47176/jame.42.2.1013
Abstract
Prevention of infection and bioactivity of implantable parts in the body is one of the most important issues investigated in medical research in recent years. In this regard, researchers have conducted many studies in order to increase the bioactivity of implantable parts in the body. Increasing the bioactivity of these parts has been done in different ways, while coating the surface of the parts is considered as one of the best methods in this field. In this research, simultaneous coating of iron oxide nanoparticles (magnetite) along with 45S5 bioactive glass on AISI 316 stainless steel substrate was deposited by electrophoretic method to increase the bioactivity and the possibility of hyperthermic applications. X-ray diffraction analysis confirmed the presence of both iron oxide nanoparticles and bioactive glass. Electron microscope was employed to study the coating surface. Conducting surface investigations by surface roughness and wetting angle measurements, it was shown that the roughness of the coated surface was 49.2±1 µm and the wetting angle of this coating was obtained to be 49°. The results declared that this coating had a surface with medium roughness and hydrophilic properties, which was of great importance for bioactivity performance. Investigating the magnetic properties of the coating, magnetometric evaluation was performed on the synthesized samples. The saturation magnetization and the Hc parameter values of the coating were obtained to be 20.2 emu/g and 89 Gauss, respectively.
Keywords
Coating
Bio-active
Magnetic particles
Iron oxide
Electrophoretic
Bioglass
Subjects
  1. Azzouz I, Faure J, Khlifi K, Cheikh Larbi A, Benhayoune H. Electrophoretic Deposition of 45S5 Bioglass® Coatings on the Ti6Al4V Prosthetic Alloy with Improved Mechanical Properties. Coatings. 2020 Dec 6;10(12):1192.DOI: 10.3390/coatings10121192
  2. Sivakumar M, Rajeswari S, Thulasiraman V. Metallographic investigation of a failed stainless steel orthopaedic implant device. J Mater. Sci Lett. 1996;15(24):2192–4.
  3. Vafa E, Bazargan-Lari R, Bahrololoom ME. Electrophoretic deposition of polyvinyl alcohol/natural chitosan/bioactive glass composite coatings on 316L stainless steel for biomedical application. Prog. Org Coat. 2021 Feb;151:106059. DOI: 10.1016/j.porgcoat.2020.106059
  4. Bordbar Khiabani A, Rahimi S, Yarmand B, Mozafari M. Electrophoretic deposition of graphene oxide on plasma electrolytic oxidized-magnesium implants for bone tissue engineering applications. Mater. Today Proc. 2018;5(7):15603–12. DOI: 10.1016/j.matpr.2018.04.169
  5. D’Elia A, Deering J, Clifford A, Lee BEJ, Grandfield K, Zhitomirsky I. Electrophoretic deposition of polymethylmethacrylate and composites for biomedical applications. Colloids Surf B Biointerfaces. 2020 Apr;188:110763. DOI: 10.1016/j.colsurfb.2019.110763
  6. Misch CE. Dental implant prosthetics-E-book. Elsevier Health Sciences; 2004.
  7. Chillo S, Flores S, Mastromatteo M, Conte A, Gerschenson L, Del Nobile MA. Influence of glycerol and chitosan on tapioca starch-based edible film properties. J. Food Eng. 2008;88(2):159–68.
  8. Li Y, Wang Z, Liu R. Superparamagnetic α-Fe2O3/Fe3O4 Heterogeneous Nanoparticles with Enhanced Biocompatibility. Nanomaterials. 2021 Mar 24;11(4):834. Available from: https://www.mdpi.com/ 2079-4991/11/4/834 DOI: 10.3390/nano11040834
  9. Li Z, Kawashita M, Araki N, Mitsumori M, Hiraoka M, Doi M. Magnetic SiO2 gel microspheres for arterial embolization hyperthermia. Biomedical Materials. 2010;5(6):65010. DOI: 1088/1748-6041/5/6/065010
  10. Rajan A, Sharma M, Sahu NK. Assessing magnetic and inductive thermal properties of various surfactants functionalised Fe3O4 nanoparticles for hyperthermia. Sci Rep. 2020 Sep 22;10(1):15045. DOI: 10.1038/s41598-020-71703-6
  11. Cornell RM, Schwertmann U. The iron oxides: structure, properties, reactions, occurrences, and uses. Vol. 664. Wiley-vch Weinheim; 2003.
  12. Ghazanfari MR, Shams SF, Jaafari MR, Kashefi M. Multi-successive-step pH sensitive procedure: Survey of dominant formation mechanism of therapeutic SPIONs. Ceram Int. 2019 Apr;45(5): 6030–6. DOI: 10.1016/j.ceramint.2018.12.073
  13. Sandler SE, Fellows B, Mefford OT. Best Practices for Characterization of Magnetic Nanoparticles for Biomedical Applications. Anal. Chem. 2019 Nov 19;91(22):14159–69. DOI: 10.1021/acs.analchem. 9b03518
  14. Saifullah S, Ali I, Kawish M, El-Shabasy RM, Chen L, El-Seedi HR. Chapter 12—Surface functionalized magnetic nanoparticles for targeted cancer therapy and diagnosis. Metal Nanoparticles for Drug Delivery and Diagnostic Applications, 1st ed; Elsevier: Amsterdam, The Netherlands. 2020;
  15. Moriche R, Beltrán AM, Begines B, Rodríguez-Ortiz JA, Alcudia A, Torres Y. Influence of the porosity and type of bioglass on the micro-mechanical and bioactive behavior of coated porous titanium J. Non. Cryst. Solids. 2021 Jan;551:120436. DOI: 10.1016/j.jnoncrysol.2020.120436
  16. Hench LL, Splinter RJ, Allen WC, Greenlee TK. Bonding mechanisms at the interface of ceramic prosthetic materials. J. Biomed. Mater. Res. 1971 Nov;5(6):117–41. DOI: 10.1002/jbm.820050611
  17. Fernandez de Grado G, Keller L, Idoux-Gillet Y, Wagner Q, Musset AM, Benkirane-Jessel N, Bone substitutes: a review of their characteristics, clinical use, and perspectives for large bone defects management. J. Tissue Eng. 2018 Jan 1; 9:204173141877681. DOI: 10.1177/2041731418776819
  18. Moreira CDF, Carvalho SM, Sousa RG, Mansur HS, Pereira MM. Nanostructured chitosan/gelatin/bioactive glass in situ forming
  19. hydrogel composites as a potential injectable matrix for bone tissue engineering. Mater. Chem. Phys. 2018 Oct;218:304–16. DOI: 10.1016/j.matchemphys. 2018.07.039
  20. Ali A, Ershad M, Vyas VK, Hira SK, Manna PP, Singh BN, et al. Studies on effect of CuO addition on mechanical properties and in vitro cytocompatibility in 1393 bioactive glass scaffold. Materials Science and Engineering: C. 2018 Dec;93:341–55. DOI: 10.1016/j.msec.2018.08.003
  21. Shaikh S, Kedia S, Majumdar AG, Subramanian M, Sinha S. 45S5 bioactive glass coating on Ti6Al4V alloy using pulsed laser deposition technique. Mater. Res. Express. 2020 Feb 26;6(12):125428. DOI: 10.1088/2053-1591/ab7568
  22. Vichery C, Nedelec JM. Bioactive Glass Nanoparticles: From Synthesis to Materials Design for Biomedical Applications. Materials. 2016 Apr 14;9(4):288. DOI: 10.3390/ma9040288
  23. Besrs L, Liu M. A review on fundamentals and applications of electrophoretic deposition (EPD). Prog. Mater. Sci. 2007 Jan;52(1):1–61. DOI: 10.1016/j.pmatsci.2006.07.001
  24. Van der Biest OO, Vandeperre LJ. Electrophoretic Deposition of Materials. Annual Review of Materials Science. 1999;29(1):327–52. DOI: 10.1146/annurev. matsci.29.1.327
  25. de Siqueira L, Gouveia RF, Grenho L, Monteiro FJ, Fernandes MH, Trichês ES. Highly porous 45S5 bioglass-derived glass–ceramic scaffolds by gelcasting of foams. J. Mater. Sci. 2018; 24; 53(15):10718–31. DOI: 10.1007/s10853-018-2337-x
  26. Chen W, Long T, Guo YJ, Zhu ZA, Guo YP. Magnetic hydroxyapatite coatings with oriented nanorod arrays: hydrothermal synthesis, structure and biocompatibility. J Mater. Chem. B. 2014;2(12): 1653. DOI: 10.1039/c3tb21769h
  27. Ansari M, Bigham A, Ahangar HA. Super-paramagnetic nanostructured CuZnMg mixed spinel ferrite for bone tissue regeneration. Materials Science and Engineering: C. 2019;105:110084. DOI: 10.1016/j.msec.2019.110084
  28. Boschetto F, Ngoc Doan H, Phong Vo P, Zanocco M, Zhu W, Sakai W. Antibacterial and Osteoconductive Effects of Chitosan/Polyethylene Oxide (PEO)/ Bioactive Glass Nanofibers for Orthopedic Applications. Applied Sciences 2020;10(7):2360. DOI: 10.3390/app10072360
Journal of Advanced Materials in Engineering
Volume 42, Issue 2
Summer 2023
Pages 1-13

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