Synthesis and Characterization of Silicate Calcium Phosphate Bioactive Glass Prepared by Electrospinning Method

Authors

1 1- Department of Chemistry, Faculty of Science, Maragheh University, Eastern Azerbaijan, Iran

2 2-Department of Nanotechnology and Advanced Materials, Materials and Energy Research Center, Karaj, Alborz, Iran

Abstract

Ternary (%mol) (64SiO2-31CaO-5P < sub>2O5) system of sol-gel derived bioactive glass fibers was prepared by electrospinning method. X-ray Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM) and nitrogen adsorption test (BET) analyses were performed to investigate the phase and chemical group of the composition, morphology of the surface and specific surface area of the fibers, respectively. SEM observations confirmed that the fibers were nano size. The amorphous nature and the presence of silanol groups in the composition were confirmed by XRD and FTIR, respectively. Apatite formation and biodegradability of the fibers were studied using various analyses after different days of soaking in simulated body fluid (SBF). The results affirmed the presence of apatite layers on the surface of the fibers. Cell culture evaluation indicated that MG-64 human osteoblast-like cells were attached and spread well on the surface. Furthermore, cell viability and cell growth demonstrated that the cells were grown and reproduced well on the fibers.

Keywords

References

1. Waterstrat, R.M., \"Brushing Up on the History of Intermetallics in Dentistry\", Journal of the Minerals, Metals &amp; Materials Society, Vol. 42, pp. 8-14, 1990.
2. Hench, L.L., \"The Story of Bioglass\", Journal of Materials Science: Materials in Medicine, Vol. 17, pp. 967-978, 2006.
4. Nabian, N., Jahanshahi, M. and Rabiee., S.M., \"Synthesis of Nano-Bioactive Glass-Ceramic Powders and its in vitro Bioactivity M. Study in Bovine Serum Albumin Protein\", Journal of Molecular Structure, Vol. 998, pp. 37-41, 2011.
5. Li, R., Clark, A.E. and Hench, L.L., \"An Investigation of Bioactive Glass Powders by Sol-Gel Processing\", Journal of Applied Biomaterial, Vol. 2, pp. 231-239, 1991.
6. Cao, W. and Hench, L.L., \"Bioactive Materials\", Ceramics International, Vol. 22, pp. 493-507, 1996.
7. Salehi, S. and Fathi, M.H., \"Fabrication and Characterization of Sol-Gel Derived Hydroxyapatite/ Zirconia Composite Nanopowders with Various Yttria Contents\", Ceramics International, Vol. 36, pp.1659-1667, 2010.
8. Boccaccini, A.R., Tissue Engineering Using Ceramics and Polymers, CRC Press, 2007.
9. Nezafati, N., Moztarzadeh, F., Hesaraki, S. and Mozafari, M., \"Synergistically Reinforcement of a Self-Setting Calcium Phosphate Cement with Bioactive Glass Fibers\", Ceramics International,
Vol. 37, pp. 927-934, 2011.
10. Nezafati N., Moztarzadeh F., Hesaraki S., Moztarzadeh Z. and Mozafari M., \"Biological Response of a Recently Developed Nanocomposite Based on Calcium Phosphate Cement and Sol-Gel Derived Bioactive Glass Fibers as Substitution of Bone Tissues\", Ceramics International, Vol. 39,
pp. 289-297, 2014.
11. Ramakrishna, S., An Introduction to Electrospinning and Nanofibers, World Scientific, Singapore, 2005.
12. Heikkil, P. and Harlin, A., \"Parameter Study of Electrospinning of Polyamide-6\", European Polymer Journal, Vol. 44, pp. 3067-3079, 2008.
13. Zuo, W., Zhu, M., Yang, W., Yu, H., Chen, Y. and Zhang, Y., \"Experimental Study on Relationship between Jet Instability and Formation of Beaded Fibers during Electrospinning\", Polymer Engineering &amp; Science, Vol. 45, pp. 704-709, 2005.
14. Tsou, P., Electrospinning of Silica Nanofibers Characterization and Application to Biosensing, A&amp;M University, Texas, 2010.
15. He, J.H., Liu, Y. and Wan, Y.Q., Electrospun Nanofibers and their Application, p. 251, Shawbury, UK, 2008.
16. Kokubo, T., Kushitani, H., Sakka, S., Kitsugi, T. and Yamamuro., T., \"Solutions Able to Reproduce in vivo Surface-Structure Changes in Bioactive Glass-Ceramic A-W3\", Journal of Biomedical Materials Research, vol.24, pp. 721-734,1990.
17. Balamurugan, A., Sockalingum, G., Michel, J., Faur, J., Banchet, V., Wortham, L., Bouthors, S., Laurent-Maquin, D. and Balossier, G., \" Synthesis and Characterisation of Sol Gel Derived Bioactive Glass for Biomedical Applications\", Materials Letter,
Vol. 60, pp. 3752-3757, 2006.
18. Kim, I.S. and Kumta, P.N., \"Sol-gel Synthesis and Characterization of Nanostructured Hydroxyapatite powder\", Materials Science and Engineering: B,
Vol. 111, pp. 232-236, 2004.
19. Skokubo, T., Bioceramics and their Clinical Applications, Wood head Pub. and Maney Pub., Cambridge, 2008.
20. Li, N., Jie, Q., Zhu, S. and Wang, R., \"A New Route to Prepare Macroporous Bioactive Sol Gel Glasses with High Mechanical Strength\", Materials Letter, Vol. 58, pp. 2747-2750, 2004.
21. Seeman, E., Devogelaer, J.P., Lorenc, R., Spector, T., Brixen, K., Balogh, A., Stucki, G. and Reginster, J.Y., \"Strontium Ranelate Reduces the Risk of Vertebral Fractures in Patients with Osteopenia\", Journal of Bone and Mineral Research, Vol. 23,
pp. 433-438, 2008 .
22. Panzavolta, S., Torricelli, P., Sturba, L., Bracci, B., Giardino, R. and Bigi., A., \"Setting Properties and in Vitro Bioactivity of Strontium-Enriched Gelatin-Calcium Phosphate Bone Cements\", Journal of Biomedical Materials Research: A, Vol. 84, pp. 965-972, 2008
23. Pietak, A.M., Reid, J.W., Stott, M.J. and Sayer., M., \"Silicon Substitution in the Calcium Phosphate Bioceramics\", Biomaterials, Vol. 28, pp. 4023-4032, 2007.
24. Phan, P.V., Grzanna, M., Chu, J., Polotsky, A.,
El-Ghannam, A., Heerden, D.V., Hungerford, D.S. and Frondoza, C.G., \"The Effect of Silica-Containing Calcium-Phosphate Particles on Human Osteoblasts in Vitro\", Journal of Biomedical Materials Research: A, Vol. 67, pp.1001-1008, 2003
25. Buehler, J., Chappuis, P., Saffar, J.L., Tsouderos, Y. and Vignery, A., \"Strontium Ranelate Inhibits Bone Resorption while Maintaining Bone Formation in Alveolar Bone in Monkeys (Macacafascicularis)\", Bone, Vol. 29, pp. 176-179, 2001.
Journal of Advanced Materials in Engineering (Esteghlal)
Volume 35, Issue 1
June 2016
Pages 57-69

Files

Share

How to cite

Statistics

ارتقاء امنیت وب با وف ایرانی