اندازه‌گیری ضریب انباشت دز پرتوهای گامای چشمه سزیم در ژل پلیمر حاوی نانوذرات نقره در غلظت‌های مختلف

نوع مقاله : مقاله پژوهشی

نویسندگان

دانشکده فیزیک و مهندسی هسته ای، دانشگاه صنعتی شاهرود، شاهرود، کد پستی: 95161-36199، سمنان، ایران

چکیده

مقدمه و اهداف: امروزه استفاده از پرتوهای یونیزان جهت درمان تومورهای سرطانی به‌طور مداوم در حال پیچیده‌ترشدن و دگرگون‌شدن هستند. در این تحقیق، اثر نانوذرات نقره در کمیت ضریب انباشت دز در ژل پلیمر PAGAS، به‌عنوان یک ماده نگهدارنده نانوذرات نقره، به‌منظور بررسی تاثیر نانوذرات نقره در پرتودرمانی و ساخت حفاظ مناسب (سبک، غیرسمی و انعطاف‌پذیر)، موردمطالعه قرار گرفته است. 
مواد و روش‌ها: منبع تولید پرتو گاما چشمه سزیم است. نانوذرات نقره به صورت محلول و با غلظت ppm 1000 است. ضریب انباشت دز توسط آشکارساز NaI(TL) اندازه‌گیری می‌شود. 
یافته‌ها: برای بررسی اثر نانوذرات نقره بر ضریب انباشت دز، از نانوذرات نقره از غلظت صفر تا هشت میلی‌مولار در دو نمونه از ژل پلیمر که یکی در ارتفاع یک سانتی‌متر و دیگری در ارتفاع  سه سانتی‌متر قرار دارد، استفاده شده است. از غلظت صفر تا دو میلی‌مولار نانوذرات نقره، ضریب انباشت دز روند افزایشی دارد؛ به‌طوری که در نمونه‌هایی با ارتفاع یک و سه سانتی‌متر، به ترتیب به بیشینه مقدار 1/092 و 1/119 می‌رسد و از غلظت دو تا هشت میلی‌مولار نانوذرات نقره، ضریب انباشت دز روند کاهشی دارد؛ به‌طوری که در نمونه‌هایی با ارتفاع یک و سه سانتی‌متر، به ترتیب به کمینه مقدار 1/010 و 1/091 می‌رسیم.  
نتیجه‌گیری: حضور نانوذرات نقره در ژل پلیمر، باعث افزایش برهمکنش پرتوها می‌شود که این افزایش برهمکنش پرتوها، در بافت سرطانی منجر به تخریب بیشتر بافت سرطانی شده و در حفاظ باعث تضعیف بیشتر پرتوها می‌گردد.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

Measurement of the Dose Buildup Factor of Cesium Source Gamma Rays in Polymer Gel Containing Silver Nanoparticles in Different Concentrations

نویسندگان [English]

  • Ammar Vahedian Movahed
  • Hossein Tavakoli-Anbaran
Faculty of Physics and Nuclear Engineering, Shahrood University of Technology, Shahrood 36199-95161, Semnan, Iran
چکیده [English]

Introduction and Objectives: Nowadays, the use of ionizing radiation for the treatment of cancerous tumors is becoming increasingly sophisticated and evolving. In this study, the effect of silver nanoparticles on the dose buildup factor in PAGAS polymer gel—as a medium for holding silver nanoparticles—was investigated to evaluate their impact on radiotherapy and to develop suitable shielding materials that are lightweight, non-toxic, and flexible.
Materials and Methods: The gamma ray source is a cesium source. Silver nanoparticles are in solution at a concentration of 1000 ppm. The dose buildup factor is measured by a NaI(TL) detector.
Results: To investigate the effect of silver nanoparticles on the dose buildup factor, silver nanoparticles from a concentration of 0 to 8 mM were used in two samples of polymer gel, one at a height of 1 cm and the other at a height of 3 cm. From a concentration of 0 to 2 mM of silver nanoparticles, the dose buildup factor has an increasing trend, reaching a maximum value of 1.092 and 1.119 in samples with a height of 1 and 3 cm, respectively, and from a concentration of 2 to 8 mM of silver nanoparticles, the dose buildup factor has a decreasing trend. reaching a minimum value of 1.010 and 1.091 In samples with a height of 1 and 3 cm, respectively.
Conclusion: The presence of silver nanoparticles in the polymer gel increases the interaction of the rays, which in cancerous tissue leads to further destruction of the cancerous tissue and in the shield causes further attenuation of the rays.

کلیدواژه‌ها [English]

  • Buildup factor
  • Radiotherapy
  • Gamma ray
  • Cesium source
  • Protection
  • Polymer gel
  • Silver nanoparticles

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مواد پیشرفته در مهندسی
دوره 44، شماره 4
(شماره پیاپی 51)
1404
صفحه 93-108

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